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WILMS'TUMOR (NEPHROBLASTOMA


Wilms' tumor most often affects children ages 3 to 4 and becomes much less common after age 5.

Wilms' tumor most often occurs in just one kidney, though it can sometimes be found in both kidneys at the same time.



Pathophysiology

It's not clear what causes Wilms' tumor, but in rare cases, heredity may play a role.

Cancer begins when cells develop errors in their DNA. The errors allow the cells to grow and divide uncontrollably and to go on living when other cells would die. The accumulating cells form a tumor. In Wilms' tumor, this process occurs in the kidney cells.


Diagnosis

▪️Physical examination

▪️Blood & urine tests

▪️Imaging tests


Treatment

✔️Surgery

✔️Chemotherapy

✔️Radiotherapy

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